KD-Validated Farnesyl Diphosphate Synthase Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Farnesyl Diphosphate Synthase Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:FDPS; Farnesyl Diphosphate Synthase; Farnesyl Pyrophosphate Synthetase, Dimethylallyltranstransferase, Geranyltranstransferase; (2E,6E)-Farnesyl Diphosphate Synthase; Farnesyl Pyrophosphate Synthase; FPP Synthase; FPS; Dimethylallyltranstransferase; Geranyltranstransferase; FPP Synthetase; EC 2.5.1.10; EC 2.5.1.1; KIAA1293; POROK9; FPPS Background: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008] Research Area: Cardiovascular,Signal Transduction,Cancer,Metabolism