KD-Validated FLNA Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated FLNA Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:2,000-1:10,000; FC 1:200-1:2,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:FLNA; Filamin A; ABP-280; FLN1; FLN; Endothelial Actin-Binding Protein; Actin Binding Protein 280; Non-Muscle Filamin; Filamin A, Alpha; Alpha-Filamin; Filamin-A; Filamin-1; FLN-A; OPD1; OPD2; Filamin A, Alpha (Actin Binding Protein 280); Epididymis Secretory Sperm Binding Protein; Actin-Binding Protein 280; Alpha Filamin; EC 2.1.1.43; EC 6.3.4.4; ABPX; CSBS; CVD1; FGS2; NHBP; XLVD; XMVD; FMD; MNS; OPD Background: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009] Research Area: Signal Transduction,Neuroscience