KD-Validated GALT Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated GALT Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:GALT; Galactose-1-Phosphate Uridylyltransferase; UDP-Glucose--Hexose-1-Phosphate Uridylyltransferase; Gal-1-P Uridylyltransferase; Galactose-1-Phosphate Uridyl Transferase; EC 2.7.7.12 Background: Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] Research Area: Signal Transduction,Cancer,Metabolism