KD-Validated GATA2/GATA3 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated GATA2/GATA3 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:GATA2; GATA Binding Protein 2; NFE1B; Endothelial Transcription Factor GATA-2; GATA-Binding Protein 2; MONOMAC; IMD21; DCML; GATA3; GATA Binding Protein 3; HDR; Trans-Acting T-Cell-Specific Transcription Factor GATA-3; GATA-Binding Factor 3; GATA-Binding Protein 3; HDRS Background: GATA3: This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009] GATA2: This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009] Research Area: Immunology,Epigenetics and Nuclear Signaling,Stem Cells,Developmental Biology