KD-Validated GEMIN2 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated GEMIN2 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:GEMIN2; Gem Nuclear Organelle Associated Protein 2; SIP1; Survival Of Motor Neuron Protein Interacting Protein 1; Gem-Associated Protein; Component Of Gems; Gemin-2; Survival Of Motor Neuron Protein-Interacting Protein 1; Gem (Nuclear Organelle) Associated Protein 2; SMN Interacting Protein 1-Delta; SMN-Interacting Protein 1; SIP1-Delta Background: This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011] Research Area: Neuroscience