KD-Validated Gli3 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Gli3 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:GLI Family Zinc Finger 3; PAP-A; PAPA1; PPDIV; PAPA; PAPB; ACLS; Glioma-Associated Oncogene Family Zinc Finger 3; GLI-Kruppel Family Member GLI3;Transcriptional Activator GLI3; Zinc Finger Protein GLI3; Oncogene GLI3; GLI3-190; GLI3FL; GCPS; PHS; Greig Cephalopolysyndactyly Syndrome; GLI3 Full-Length Protein; GLI3 Form Of 190 KDa; DNA-Binding Protein Background: This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008] Research Area: Epigenetics and Nuclear Signaling,Neuroscience,Stem Cells