KD-Validated Glutamate-Ammonia Ligase Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Glutamate-Ammonia Ligase Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:Glutamate-Ammonia Ligase; Glutamine Synthetase; GLNS; Palmitoyltransferase GLUL; EC 6.3.1.2; GS; Glutamate-Ammonia Ligase (Glutamine Synthase); Cell Proliferation-Inducing Protein; Proliferation-Inducing Protein; Glutamate--Ammonia Ligase; Glutamate Decarboxylase; Glutamine Synthase; EC 2.3.1.225; PIG43; PIG59 Background: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] Research Area: Neuroscience