KD-Validated GRK2 Rabbit Polyclonal Antibody

Description

EnkiLife offers the KD-Validated GRK2 Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000 Alternative Names of Immunogen:GRK2; G Protein-Coupled Receptor Kinase 2; BARK1; ADRBK1; Beta-Adrenergic Receptor Kinase 1; EC 2.7.11.15; Beta-ARK-1; Adrenergic, Beta, Receptor Kinase 1; G-Protein Coupled Receptor Kinase 2; Adrenergic Beta Receptor Kinase 1; BETA-ARK1; EC 2.7.11 47; BARK Background: This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017] Research Area: Neuroscience,Signal Transduction