KD-Validated Growth Differentiation Factor 3 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Growth Differentiation Factor 3 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000 Alternative Names of Immunogen:GDF3; Growth Differentiation Factor 3; Growth/Differentiation Factor 3; MCOPCB6; MCOP7; GDF-3; KFS3 Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016] Research Area: Signal Transduction,Stem Cells