KD-Validated HDAC3 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated HDAC3 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:Histone Deacetylase 3; RPD3-2; HD3 KDAC3; RPD3; Protein Deacetylase HDAC3; Protein Deacylase HDAC3; EC 3.5.1.98; SMAP45; EC 3.5.1.- Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008] Research Area: Epigenetics and Nuclear Signaling,Stem Cells,Cancer,Metabolism