KD-Validated HDAC4 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated HDAC4 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:Histone Deacetylase 4; HD4; KIAA0288; HDAC-A; HA6116; HDAC-4; HDACA; EC 3.5.1.98; BDMR; Brachydactyly-Mental Retardation Syndrome; Histone Deacetylase A; NEDCHID; NEDCHF; AHO3 Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008] Research Area: Epigenetics and Nuclear Signaling,Stem Cells,Cardiovascular,Neuroscience