KD-Validated Histone Deacetylase 9 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Histone Deacetylase 9 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:4,000-1:20,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:HDAC9; Histone Deacetylase 9; HDAC7B; MITR; HD7; KIAA0744; HDAC; Histone Deacetylase 7B; EC 3.5.1.98; HDAC; HD7b; HDRP; HD9; MEF-2 Interacting Transcription Repressor (MITR) Protein; MEF2-Interacting Transcription Repressor MITR; Histone Deacetylase 4/5-Related Protein; Histone Deacetylase-Related Protein; HDAC9FL; ARCND4; HDAC9B Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq, Jul 2008] Research Area: Epigenetics and Nuclear Signaling,Cardiovascular,Neuroscience