KD-Validated Histone Deacetylase 8 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Histone Deacetylase 8 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:4,000-1:20,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:HDAC8; Histone Deacetylase 8; HDACL1; KDAC8; RPD3; Protein Decrotonylase HDAC8; Histone Deacetylase-Like 1; Protein Deacetylase HDAC8; MRXS6; HD8; WTS; Wilson-Turner X-Linked Mental Retardation Syndrome; EC 3.5.1.98; EC 3.5.1.-; CDA07; CDLS5 Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] Research Area: Epigenetics and Nuclear Signaling,Stem Cells,Cardiovascular,Neuroscience