KD-Validated Hsp22 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Hsp22 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,M and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:HSPB8; Heat Shock Protein Family B (Small) Member 8; E2IG1; HSP22; CMT2L; H11; Small Stress Protein-Like Protein HSP22; Heat Shock 27kDa Protein 8; Heat Shock 22kDa Protein 8; Heat Shock Protein Beta-8; E2-Induced Gene 1 Protein; Alpha-Crystallin C Chain; Protein Kinase H11; HSPB8-N1; HSPB8-N2; DHMN2; HMN2A; CRYAC; HspB8; HMN2 Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008] Research Area: Signal Transduction,Neuroscience