KD-Validated Hydroxymethylbilane Synthase Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Hydroxymethylbilane Synthase Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,M and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:HMBS; Hydroxymethylbilane Synthase; Porphobilinogen Deaminase; PBGD; UPS; Porphyria, Acute; Chester Type; Pre-Uroporphyrinogen Synthase; Uroporphyrinogen I Synthase; EC 2.5.1.61; PBG-D; PORC; Uroporphyrinogen I Synthetase Background: This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Research Area: Signal Transduction,Cell Biology,Metabolism