KD-Validated IMPDH2 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated IMPDH2 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:IMPDH2; Inosine Monophosphate Dehydrogenase 2; IMP (Inosine 5'-Monophosphate) Dehydrogenase 2; Inosine-5'-Monophosphate Dehydrogenase Type II; Inosine-5'-Monophosphate Dehydrogenase 2; IMP Dehydrogenase II; EC 1.1.1.205; IMPDH-II; IMPDH 2; IMPD 2; IMPD2; IMP (Inosine Monophosphate) Dehydrogenase 2; Inosine Monophosphate Dehydrogenase Type II; Epididymis Secretory Sperm Binding Protein; Inosine 5' Phosphate Dehydrogenase 2; IMP Dehydrogenase 2; IMP Oxireductase 2 Background: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008] Research Area: Signal Transduction,Cancer,Metabolism