KD-Validated Interferon Regulatory Factor 6 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Interferon Regulatory Factor 6 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:IRF6; Interferon Regulatory Factor 6; OFC6; VWS1; LPS; VWS; Van Der Woude Syndrome; IRF-6; PPS1; PIT; PPS Background: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011] Research Area: Immunology,Epigenetics and Nuclear Signaling,Stem Cells