KD-Validated Kinesin Associated Protein 3 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Kinesin Associated Protein 3 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:KIFAP3; Kinesin Associated Protein 3; SMAP; KAP3; Kinesin-Associated Protein 3; KAP-1; FLA3; Smg GDS-Associated Protein; KAP-3; Small G Protein GDP Dissociation Stimulator; DJ190I16.1; Smg GDS; Smg-GDS; KIF3AP Background: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] Research Area: Epigenetics and Nuclear Signaling