KD-Validated L1 Cell Adhesion Molecule Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated L1 Cell Adhesion Molecule Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:L1CAM; L1 Cell Adhesion Molecule; NCAM-L1; CAML1; Neural Cell Adhesion Molecule L1; CD171; MIC5; Antigen Identified By Monoclonal Antibody R1; N-CAM-L1; HSAS1; HSAS; MASA; SPG1; S10; CD171 Antigen; N-CAML1; HYCX Background: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013] Research Area: Signal Transduction,Neuroscience