KD-Validated Lamin B2 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Lamin B2 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,M and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:LMNB2; Lamin B2; LMN2; Lamin-B2; Epididymis Secretory Sperm Binding Protein; Lamin B3; MCPH27; LAMB2; EPM9 Background: This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy. [provided by RefSeq, May 2012] Research Area: Cell Biology,Epigenetics and Nuclear Signaling,Tags & Cell Markers,Signal Transduction,Cancer