KD-Validated LDL Receptor Related Protein 1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated LDL Receptor Related Protein 1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:LRP1; LDL Receptor Related Protein 1; APOER; Alpha-2-Macroglobulin Receptor; IGFBP3R1; IGFBP-3R; LRP1A; CD91; A2MR; LRP; APR; Prolow-Density Lipoprotein Receptor-Related Protein 1; Low Density Lipoprotein Receptor-Related Protein 1; Apolipoprotein E Receptor; Transforming Growth Factor-β Receptor Type V; TbetaR-V/LRP-1/IGFBP-3 Receptor; Type V Tgf-Beta Receptor; CD91 Antigen; EC 3.4.21.9; EC 1.1.1.94; IGFBP3R; TGFBR5; LRP-1; KPA Background: This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015] Research Area: Neuroscience,Cardiovascular,Cell Biology,Signal Transduction,Metabolism,Cancer