KD-Validated LDL Receptor Related Protein 8 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated LDL Receptor Related Protein 8 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:LRP8; LDL Receptor Related Protein 8; APOER2; LRP-8; HSZ75190; MCI1; Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor; Low-Density Lipoprotein Receptor-Related Protein 8; Apolipoprotein E Receptor 2; ApoE Receptor 2 Background: This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011] Research Area: Neuroscience,Signal Transduction,Cardiovascular,Metabolism