KD-Validated LGI1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated LGI1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:LGI1; Leucine Rich Glioma Inactivated 1; Epitempin-1; EPITEMPIN; IB1099; ETL1; EPT; Leucine-Rich Glioma-Inactivated Protein 1; Epilepsy, Partial; ADPAEF; ADPEAF; ADLTE Background: This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] Research Area: Neuroscience,Epigenetics and Nuclear Signaling