KD-Validated LIN28A Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated LIN28A Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:LIN28A; Lin-28 Homolog A; ZCCHC1; CSDD1; LIN-28; LIN28; Zinc Finger CCHC Domain-Containing Protein 1; Protein Lin-28 Homolog A; FLJ12457; Lin-28A; Zinc Finger, CCHC Domain Containing 1; Lin-28 Homolog (C. Elegans); RNA-Binding Protein LIN-28 Background: This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015] Research Area: Epigenetics and Nuclear Signaling