KD-Validated LMAN1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated LMAN1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:LMAN1; Lectin, Mannose Binding 1; ERGIC53; ERGIC-53; MCFD1; FMFD1; F5F8D; MR60; Gp58; Endoplasmic Reticulum-Golgi Intermediate Compartment Protein 53; ER-Golgi Intermediate Compartment 53 KDa Protein; Intracellular Mannose-Specific Lectin MR60; Protein ERGIC-53; Coagulation Factor V-Factor VIII Combined Deficiency; Lectin, Mannose-Binding, 1; Lectin Mannose-Binding 1; GP58 Background: The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. [provided by RefSeq, Jul 2015] Research Area: Signal Transduction