KD-Validated MacroH2A.1 Histone Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated MacroH2A.1 Histone Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:MACROH2A1; MacroH2A.1 Histone; H2AFY; Medulloblastoma Antigen MU-MB-50.205; H2A Histone Family Member Y; Core Histone Macro-H2A.1; Histone MacroH2A1; Histone H2A.Y; MacroH2A1.2; H2A/Y; MH2A1; H2A Histone Family, Member Y; Histone MacroH2A1.1; Histone MacroH2A1.2; MACROH2A1.1; MACROH2A1.2; H2AF12M; H2A.Y Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015] Research Area: Epigenetics and Nuclear Signaling