KD-Validated Malate Dehydrogenase 1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Malate Dehydrogenase 1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:MDH1; Malate Dehydrogenase 1; Malate Dehydrogenase 1, NAD (Soluble); Aromatic Alpha-Keto Acid Reductase; Malate Dehydrogenase, Cytoplasmic; Cytosolic Malate Dehydrogenase; EC 1.1.1.37; MDHA; KAR; Epididymis Secretory Protein Li 32; Malate Dehydrogenase, Peroxisomal; Diiodophenylpyruvate Reductase; Soluble Malate Dehydrogenase; EC 1.1.1.96; HEL-S-32; MGC:1375; EIEE88; DEE88; MDH-S; MOR2 Background: This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6. [provided by RefSeq, Feb 2016] Research Area: Signal Transduction,Cancer,Metabolism