KD-Validated Matrix Metallopeptidase 14 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Matrix Metallopeptidase 14 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:MMP14; Matrix Metallopeptidase 14; MT1-MMP; Matrix Metallopeptidase 14 (Membrane-Inserted); Membrane-Type-1 Matrix Metalloproteinase; Membrane Type 1 Metalloprotease; Matrix Metalloproteinase-14; EC 3.4.24.80; MT-MMP 1; MMP-14; MMP-X1; MT1MMP; MTMMP1; Matrix Metalloproteinase 14 (Membrane-Inserted); Membrane Type 1-Matrix Metalloproteinase; Membrane-Type Matrix Metalloproteinase 1; EC 3.4.24; MT-MMP; WNCHRS Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008] Research Area: Cardiovascular,Signal Transduction,Cancer,Cell Biology,Metabolism,Neuroscience