KD-Validated Methionyl Aminopeptidase 2 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Methionyl Aminopeptidase 2 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:METAP2; Methionyl Aminopeptidase 2; MNPEP; MAP2; P67; Initiation Factor 2-Associated 67 KDa Glycoprotein; Methionine Aminopeptidase 2; Peptidase M; P67eIF2; Testicular Tissue Protein Li 17; EIF-2-Associated P67 Homolog; Peptidase M 2; EC 3.4.11.18; P67EIF2; MetAP 2; MAP 2 Background: The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] Research Area: Signal Transduction,Metabolism