KD-Validated Mitogen-Activated Protein Kinase 1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Mitogen-Activated Protein Kinase 1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:MAPK1; Mitogen-Activated Protein Kinase 1; ERK2; Extracellular Signal Regulated Kinase 2; P41mapk; MAPK; PRKM1; PRKM2; ERK; Mitogen-Activated Protein Kinase 2; MAP Kinase 1; MAP Kinase 2; EC 2.7.11.24; P42-MAPK; MAPK 2; ERK-2; ERT1; Protein Tyrosine Kinase ERK2; MAP Kinase Isoform P42; EC 2.7.11; P42MAPK; MAPK 1; NS13; P38; P40; P41 Background: This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014] Research Area: Neuroscience,Signal Transduction,Stem Cells