KD-Validated MYD88 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated MYD88 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:MYD88 Innate Immune Signal Transduction Adaptor; Myeloid Differentiation Primary Response Protein MyD88; Myeloid Differentiation Primary Response Gene (88); Myeloid Differentiation Primary Response 88; TLR Adaptor MYD88; Mutant Myeloid Differentiation Primary Response 88; MYD88D; IMD68; WM1 Background: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] Research Area: Signal Transduction,Cardiovascular,Immunology