KD-Validated NDUFA1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated NDUFA1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:NDUFA1; NADH:Ubiquinone Oxidoreductase Subunit A1; CI-MWFE; MWFE; NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 1, 7.5kDa; NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Subunit 1; NADH-Ubiquinone Oxidoreductase MWFE Subunit; NADH:Ubiquinone Oxidoreductase (Complex 1); Complex I MWFE Subunit; Type I Dehydrogenase; NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 1 (7.5kD, MWFE); Complex I-MWFE; MC1DN12; ZNF183 Background: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008] Research Area: Cardiovascular,Neuroscience