KD-Validated NEFL Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated NEFL Mouse Monoclonal Antibody. This antibody reacts with Human and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:400-1:2,000 Alternative Names of Immunogen:NEFL; Neurofilament Light Chain; NF68; NFL; PPP1R110; CMT1F; CMT2E; Protein Phosphatase 1, Regulatory Subunit 110; Neurofilament, Light Polypeptide 68kDa; Neurofilament Light Polypeptide; Neurofilament Triplet L Protein; NF-L; Light Molecular Weight Neurofilament Protein; Neurofilament Protein, Light Chain; Neurofilament, Light Polypeptide; 68 KDa Neurofilament Protein; Neurofilament Subunit NF-L; Neurofilament Light; CMTDIG Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008] Research Area: Developmental Biology,Neuroscience,Signal Transduction,Stem Cells