KD-Validated NF2 / Merlin Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated NF2 / Merlin Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:NF2; NF2, Moesin-Ezrin-Radixin Like (MERLIN) Tumor Suppressor; SCH; Schwannomin; Merlin; BANF; ACN; Neurofibromin 2 (Bilateral Acoustic Neuroma); Bilateral Acoustic Neurofibromatosis; Moesin-Ezrin-Radixin-Like Protein; Moesin-Ezrin-Radixin Like; Neurofibromin-2 ; Schwannomerlin; Merlin-1; Moesin-Ezrin-Radizin-Like Protein; Neurofibromin 2 (Merlin); MERLIN-1; MERLIN; SWNV Background: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that link cytoskeletal components with proteins in the cell membrane. The encoded protein is involved in regulation of contact-dependent inhibition of cell proliferation and functions in cell-cell adhesion and transmembrane signaling. The encoded protein has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics, and proteins involved in regulating ion transport. Disruption of this protein's function has been implicated in tumorigenesis and metastasis. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. [provided by RefSeq, May 2022] Research Area: Neuroscience,Signal Transduction,Epigenetics and Nuclear Signaling,Cancer