KD-Validated NHERF1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated NHERF1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:NHERF1; NHERF Family PDZ Scaffold Protein 1; NHERF-1; NHERF; EBP50; SLC9A3R1; NHE-RF; Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1; Na(+)/H(+) Exchange Regulatory Cofactor NHE-RF1; Ezrin-Radixin-Moesin-Binding Phosphoprotein 50; Regulatory Cofactor Of Na(+)/H(+) Exchanger; Na(+)/H(+) Exchange Regulatory Cofactor 1; SLC9A3 Regulator 1; Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Isoform 3 Regulatory Factor 1; Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Isoform 3 Regulator 1; Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Member 3 Regulator 1; Solute Carrier Family 9 Isoform A3 Regulatory Factor 1; Ezrin-Radixin-Moesin Binding Phosphoprotein-50; Sodium-Hydrogen Exchanger Regulatory Factor 1; Na+/H+ Exchange Regulatory Co-Factor; NPHLOP2 Background: This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009] Research Area: Tags & Cell Markers,Signal Transduction,Cancer