KD-Validated NME1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated NME1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:NME1; NME/NM23 Nucleoside Diphosphate Kinase 1; NM23-H1; NDPKA; NM23; Non-Metastatic Cells 1, Protein (NM23A) Expressed In; Tumor Metastatic Process-Associated Protein; Metastasis Inhibition Factor Nm23; Nucleoside Diphosphate Kinase A; Granzyme A-Activated DNase; NDP Kinase A; EC 2.7.4.6; GAAD; Epididymis Secretory Sperm Binding Protein; NDPK-A; NDK;NDKA; AWD; NBS; NB Background: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008] Research Area: Epigenetics and Nuclear Signaling