KD-Validated NR2C2 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated NR2C2 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:Nuclear Receptor Subfamily 2 Group C Member 2; TAK1; TR4; Orphan Nuclear Receptor TAK1; Orphan Nuclear Receptor TR4; TR2R1; HTAK1; Nuclear Receptor Subfamily 2, Group C, Member 2; Testicular Nuclear Receptor 4; Nuclear Hormone Receptor TR4; Testicular Receptor 4; Orphan Receptor TR4 Background: This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] Research Area: Epigenetics and Nuclear Signaling