KD-Validated Nuclear Factor Kappa B Subunit 2 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Nuclear Factor Kappa B Subunit 2 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:NFKB2; Nuclear Factor Kappa B Subunit 2; P49/P100; LYT-10; NF-KB2; P52; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 2 (P49/P100); Lymphocyte Translocation Chromosome 10 Protein; Nuclear Factor NF-Kappa-B P100 Subunit; DNA-Binding Factor KBF2; Oncogene Lyt-10 3 4; LYT10; P105; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells; Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells; Nuclear Factor NF-Kappa-B P52 Subunit; Nuclear Factor Kappa-B, Subunit 2; Transcription Factor NFKB2; NFKB, P52/P100 Subunit; CVID10; Lyt10; P100 Background: This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] Research Area: Cell Biology,Signal Transduction,Epigenetics and Nuclear Signaling,Cancer