KD-Validated Oxoglutarate Receptor 1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Oxoglutarate Receptor 1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:OXGR1; Oxoglutarate Receptor 1; P2RY15; P2Y15; Alpha-Ketoglutarate Receptor 1; 2-Oxoglutarate Receptor 1; GPR80; GPR99; AKGR; Oxoglutarate (Alpha-Ketoglutarate) Receptor 1; G Protein-Coupled Receptor 80; G-Protein Coupled Receptor 99; P2Y-Like Nucleotide Receptor; P2Y Purinoceptor 15; P2Y-Like GPCR; Seven Transmembrane Helix Receptor; G-Protein Coupled Receptor 80; CAON2 Background: This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out of this gene leads to middle ear inflammation, changes in the mucosal epithelium, and an increase in fluid behind the eardrum, and is associated with hearing loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016] Research Area: Signal Transduction