KD-Validated Paraoxonase 2 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Paraoxonase 2 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:Paraoxonase 2; Serum Paraoxonase/Arylesterase 2; Serum Aryldialkylphosphatase 2; Aromatic Esterase 2; Paraoxonase Nirs; Arylesterase 2; A-Esterase 2; PON 2; EC 3.1.1.81; EC 3.1.1.2 Background: This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Research Area: Neuroscience,Cardiovascular,Signal Transduction,Metabolism