KD-Validated PCBD1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PCBD1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:Pterin-4 Alpha-Carbinolamine Dehydratase 1; PCD; DCOH; PCBD; 6-Pyruvoyl-Tetrahydropterin Synthase/Dimerization Cofactor Of Hepatocyte Nuclear Factor 1 Alpha (TCF1); Pterin-4 Alpha-Carbinolamine Dehydratase/Dimerization Cofactor Of Hepatocyte Nuclear Factor 1 Alpha; Phenylalanine Hydroxylase-Stimulating Protein; 4-Alpha-Hydroxy-Tetrahydropterin Dehydratase; Pterin-4-Alpha-Carbinolamine Dehydratase; Dimerizing Cofactor For HNF1; EC 4.2.1.96; PHS; Pterin-4 Alpha-Carbinolamine Dehydratase/Dimerization Cofactor Of Hepatocyte Nuclear Factor 1 Alpha (TCF1); Pterin-4a-Carbinolamine Dehydratase (Dimerization Cofactor Of Hepatic Nuclear Factor 1-Alpha); Dimerization Cofactor Of Hepatocyte Nuclear Factor 1-Alpha; Pterin-4-Alpha Carbinolamine Dehydratase; Pterin Carbinolamine Dehydratase; Dimerization Cofactor Of HNF1; DCoH Background: This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] Research Area: Signal Transduction,Epigenetics and Nuclear Signaling,Metabolism