KD-Validated PCNA Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PCNA Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:PCNA; Proliferating Cell Nuclear Antigen 2; Cyclin; DNA Polymerase Delta Auxiliary Protein; ATLD2 Background: The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008] Research Area: Cell Biology,Epigenetics and Nuclear Signaling,Tags & Cell Markers