KD-Validated PDLIM7 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PDLIM7 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:PDLIM7; PDZ And LIM Domain 7; ENIGMA; PDZ And LIM Domain 7 (Enigma); PDZ And LIM Domain Protein 7; Protein Enigma; LMP; Lim Mineralization Protein 3; LIM Mineralization Protein; LIM Domain Protein; 1110003B01Rik; LMP1; LMP3 Background: The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] Research Area: Cell Biology