KD-Validated Ubiquitin Specific Peptidase 14 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Ubiquitin Specific Peptidase 14 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:USP14; Ubiquitin Specific Peptidase 14; TGT; Ubp6; Ubiquitin Specific Peptidase 14 (TRNA-Guanine Transglycosylase); Ubiquitin Specific Protease 14 (TRNA-Guanine Transglycosylase); Ubiquitin Carboxyl-Terminal Hydrolase 14; Deubiquitinating Enzyme 14; Ubiquitin Thioesterase 14; TRNA-Guanine Transglycosylase, 60-KD Subunit; Ubiquitin-Specific Processing Protease 14; Ubiquitin-Specific-Processing Protease 14; Ubiquitin Thiolesterase 14; EC 3.4.19.12; EC 3.1.2.15 Background: This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Research Area: Cell Biology,Epigenetics and Nuclear Signaling,Neuroscience