KD-Validated Peroxiredoxin 3 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Peroxiredoxin 3 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:Peroxiredoxin 3; AOP-1; Antioxidant Protein 1; SP-22; MER5; AOP1; Thioredoxin-Dependent Peroxide Reductase, Mitochondrial; Thioredoxin-Dependent Peroxiredoxin 3; Protein MER5 Homolog; Peroxiredoxin III; Prx-III; HBC189; Epididymis Secretory Sperm Binding Protein; Peroxiredoxin-3; EC 1.11.1.24; EC 1.11.1.15; PRO1748; SCAR32; PPPCD Background: This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. [provided by RefSeq, Oct 2014] Research Area: Neuroscience,Signal Transduction,Cardiovascular,Cancer,Metabolism