KD-Validated PHGDH Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PHGDH Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:PHGDH; Phosphoglycerate Dehydrogenase; D-3-Phosphoglycerate Dehydrogenase; SERA; GDH; PDG; 2-Oxoglutarate Reductase; Malate Dehydrogenase; EC 1.1.1.95; 3-PGDH; Epididymis Secretory Protein Li 113; 3-Phosphoglycerate Dehydrogenase; EC 1.1.1.399; EC 1.1.1.37; HEL-S-113; EC 1.1.1; PHGDHD; 3PGDH; PGDH3; NLS1; PGAD; NLS; PGD Background: This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011] Research Area: Metabolism