KD-Validated Phospho-ACC(S79) Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Phospho-ACC(S79) Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:ACACA; Acetyl-CoA Carboxylase Alpha; ACC1; ACCA; Acetyl-Coenzyme A; Carboxylase Alpha; Acetyl-CoA Carboxylase 1; ACC-Alpha; HACC1; ACAC; ACACalpha; ACCalpha; Acac1; ACC; EC 6.4.1.2; ACACALPHA; ACC-ALPHA; ACCALPHA 5; ACACAD 3; ACAC1 Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Research Area: Cardiovascular,Signal Transduction,Cancer,Metabolism