KD-Validated Phospho-CDC6 (Ser106) Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Phospho-CDC6 (Ser106) Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:CDC6; Cell Division Cycle 6; CDC18L; Cell Division Control Protein 6 Homolog; Cdc18-Related Protein; CDC6-Related Protein; P62(Cdc6); HsCDC6; CDC6 (Cell Division Cycle 6, S. Cerevisiae) Homolog; CDC6 Cell Division Cycle 6 Homolog (S. Cerevisiae); Cell Division Cycle 6 Homolog (S. Cerevisiae); CDC6 Cell Division Cycle 6 Homolog; Cell Division Cycle 6 Homolog; HsCDC18; HsCdc18; MGORS5 Background: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008] Research Area: Epigenetics and Nuclear Signaling,Cell Biology