KD-Validated Phosphoglycerate Kinase 1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Phosphoglycerate Kinase 1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:PGK1; Phosphoglycerate Kinase 1; Cell Migration-Inducing Gene 10 Protein; Primer Recognition Protein; EC 2.7.2.3; PRP; PGKA; Epididymis Secretory Sperm Binding Protein Li 68p; HEL-S-68p; MIG10 Background: The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014] Research Area: Cardiovascular,Signal Transduction,Cancer,Metabolism