KD-Validated PIK3C2A Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated PIK3C2A Mouse Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500; FC 1:100-1:1,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:PIK3C2A; Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha; Phosphatidylinositol 4-Phosphate 3-Kinase C2 Domain-Containing Subunit Alpha; PI3K-C2alpha; Phosphoinositide-3-Kinase, Class 2, Alpha Polypeptide; Phosphoinositide 3-Kinase-C2-Alpha; PtdIns-3-Kinase C2 Subunit Alpha; PI3K-C2-Alpha; EC 2.7.1.154; Phosphatidylinositol-4-Phosphate 3-Kinase C2 Domain-Containing Subunit Alpha; Phosphatidylinositol-4-Phosphate 3-Kinase, Catalytic Subunit Type 2 Alpha; C2-Containing Phosphatidylinositol Kinase; PI3-K-C2(ALPHA); EC 2.7.1.137; EC 2.7.1.153; PI3-K-C2A; EC 2.7.1; OCSKD; CPK Background: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008] Research Area: Cell Biology,Signal Transduction,Immunology,Neuroscience